VGF-HM1R2-100μg / 询价
VGF-HM1R2-500μg / 询价
VGF-HM1R2-500μgx2 / 询价
Human VEGF R2/KDR Protein
Recombinant Human VEGF R2/KDR Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Glu764 [Accession | P35968-1].
The protein has a predicted MW of 84.88 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 0.1 EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The vascular endothelial growth factor receptor-2 (VEGFR-2/KDR/flk-1) functions as the primary mediator of vascular endothelial growth factor activation in endothelial cells. Regulation of VEGFR-2 expression appears critical in mitogenesis, differentiation, and angiogenesis. Transcriptional regulation of the VEGFR-2 is complex and may involve multiple putative upstream regulatory elements including E boxes.
CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73
Jackson TA, Taylor HE, Sharma D, Desiderio S, Danoff SK. Vascular endothelial growth factor receptor-2: counter-regulation by the transcription factors, TFII-I and TFII-IRD1. J Biol Chem. 2005 Aug 19;280(33):29856-63. doi: 10.1074/jbc.M500335200. Epub 2005 Jun 7. PMID: 15941713.
