A2R-HM1N1-100μg / 询价
A2R-HM1N1-100μg x 5 / 询价
A2R-HM1N1-100μg x 10 / 询价
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Human A2AR Protein-Nanodisc
Recombinant Human A2AR Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ser412 [Accession | P29274].
The protein has a predicted MW of 45.5 kDa.
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human A2AR Nanodisc, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-A2AR Antibody, mFc Tag with the EC50 of 33.1ng/ml determined by ELISA (QC Test).
Human A2AR Nanodisc, His Tag captured on CM5 Chip via Anti-his antibody can bind Anti-A2AR Antibody, mFc Tag with an affinity constant of 0.32 nM as determined in SPR assay (Biacore T200).
Loaded Anti-A2AR Antibody on Protein A-Biosensor, can bind Human A2AR Nanodisc, His Tag with an affinity constant of 4.44 nM as determined in BLI assay (Gator).
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult.
A2aR;Adenosine A2a R;ADORA 2;ADORA2;ADORA2A;RDC8
Weaver DR. A2a adenosine receptor gene expression in developing rat brain. Brain Res Mol Brain Res. 1993 Dec;20(4):313-27. doi: 10.1016/0169-328x(93)90058-w. PMID: 8114618.
