AB26-1mg / 询价
|
反应种属(Reactivities)
|
Huma/Cynomolgus/Mouse/Rat |
|
靶点(Target)
|
MASP2 |
|
同型(Isotype)
|
Human IgG1-Kappa |
|
标记(Conjugation)
|
Unconjugated |
|
表达系统(Expression System)
|
HEK293 |
|
应用(Applications)
|
ELISA/SPR |
|
分子量(Molecular Weight)
|
48.7 kDa and 22.6 kDa. |
|
稀释缓冲液
(Recommended Dilution Buffer) |
PBS (pH 7.4), contains no stabilizers or preservatives. |
|
纯化(Purification)
|
protein A |
|
无菌(Sterility)
|
0.2 μM filtered |
|
制剂(Formulation)
|
PBS, 10% glycerol (pH 7.4) |
|
内毒素(Endotoxin)
|
Less than 1 EU per μg by the LAL method. |
|
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
|
存储(Storage)
|
Valid for 12 months from date of receipt when stored at -80°C. |
Huma/Cynomolgus/Mouse/Rat
MASP2
Human IgG1-Kappa
Unconjugated
protein A
0.2 μM filtered
PBS, 10% glycerol (pH 7.4)
Less than 1 EU per μg by the LAL method.
PBS (pH 7.4), contains no stabilizers or preservatives.
<p style="line-height: 25px;">> 95% as determined by Bis-Tris PAGE<br />> 95% as determined by HPLC</p>
<p style="line-height: 25px;">Valid for 12 months from date of receipt when stored at -80°C.<br />Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.</p>
ELISA/SPR
Te MASP2 gene is located on the chromosome 1p36.23–31 and encodes two proteins, MASP-2 and Map198. Both the levels and function of MASP-2 are modulated by the single-nucleotide polymorphisms (SNPs) of the MASP2 gene. Te level of MASP-2 in plasma plays a dual role in the infection and progression of infectious diseases. Te defciency of MASP-2 in plasma has been associated with the susceptibility of HIV. By contrast, the overproduction of MASP-2 may increase the infammatory efect.
Li Z, Wang M, Zhong H, Huang X, Wu X, Zhang X, Wang J, Deng J, Chen M, Chen L, Tan H. Impact of MASP2 gene polymorphism and gene-tea drinking interaction on susceptibility to tuberculosis. Sci Rep. 2021 Mar 22;11(1):6544. doi: 10.1038/s41598-021-86129-x. PMID: 33753877; PMCID: PMC7985323.
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