AB299 | 价格

AB299-1mg / 询价

Anti-SSTR2 Antibody (Tidutamab Biosimilar)

产品信息(Product Info)
反应种属(Reactivities)

Human

靶点(Target)

SSTR2

同型(Isotype)

Human IgG1-Kappa

标记(Conjugation)

Unconjugated

纯化(Purification)

protein A

无菌(Sterility)

0.2 μM filtered

制剂(Formulation)

PBS, 10% glycerol (pH 7.4)

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

稀释缓冲液
(Recommended Dilution Buffer)

PBS (pH 7.4), contains no stabilizers or preservatives.

纯度(Purity)

<p style="line-height: 25px;">> 95% as determined by Bis-Tris PAGE<br />> 95% as determined by HPLC</p>

存储(Storage)

<p style="line-height: 25px;">Valid for 12 months from date of receipt when stored at -80°C.<br />Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.</p>

应用(Applications)

ELISA

产品数据(Assay Data)
Bis-Tris PAGE
Tidutamab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Tidutamab Biosimilar is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Human SSTR2 VLP at 5μg/ml on the plate (100μl/Well). Dose response curve for Tidutamab Biosimilar with the EC50 of 19.1ng/ml determined by ELISA. (QC Test)
背景(Background)

Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma.

文献(References)

Wu W, Zhou Y, Wang Y, Liu L, Lou J, Deng Y, Zhao P, Shao A. Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma. Front Oncol. 2020 Sep 3;10:1633. doi: 10.3389/fonc.2020.01633. PMID: 33014821; PMCID: PMC7494964.