AB602 | 价格

AB602-1mg / 询价

Anti-STEAP1 Antibody (Vandortuzumab Biosimilar)

COA MSDS
产品信息(Product Info)
反应种属(Reactivities)

Human

靶点(Target)

STEAP1

同型(Isotype)

Human IgG1-Kappa

标记(Conjugation)

Unconjugated

纯化(Purification)

protein A

无菌(Sterility)

0.2 μM filtered

制剂(Formulation)

PBS, 10% glycerol (pH 7.4)

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

稀释缓冲液
(Recommended Dilution Buffer)

PBS (pH 7.4), contains no stabilizers or preservatives.

纯度(Purity)

<p style="line-height: 25px;">> 95% as determined by Bis-Tris PAGE<br />> 95% as determined by HPLC</p>

存储(Storage)

<p style="line-height: 25px;">Valid for 12 months from date of receipt when stored at -80°C.<br />Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.</p>

应用(Applications)

ELISA

产品数据(Assay Data)
Bis-Tris PAGE
Vandortuzumab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Vandortuzumab Biosimilar is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Human STEAP1 VLP at 5 μg/ml (100μl/well) on the plate. Dose response curve for Vandortuzumab Biosimilar with the EC50 of 69.6ng/ml determined by ELISA. (QC Test)
背景(Background)

Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface protein of the STEAP family whose main function focuses on intercellular communication and cell growth. STEAP1 is is associated with tumor invasiveness and progression. It is considered a promising putative biomarker and a candidate target for prostate cancer treatment.

文献(References)

Carvalho M, Gomes RM, Moreira Rocha S, Barroca-Ferreira J, Maia CJ, Guillade L, Correa-Duarte MA, Passarinha LA, Moreira FTC. Development of a novel electrochemical biosensor based on plastic antibodies for detection of STEAP1 biomarker in cancer. Bioelectrochemistry. 2023 Aug;152:108461. doi: 10.1016/j.bioelechem.2023.108461. Epub 2023 May 9. PMID: 37192590.