ALP-HM102-UL | 价格

ALP-HM102-UL-100μg / 询价

ALP-HM102-UL-500μg / 询价

ALP-HM102-UL-500μgx2 / 询价

Human APLP2 Protein, Ultra Low Endotoxin

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human APLP2 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Gly32-Ser692 [Accession | Q06481-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 77.16 kDa. Due to glycosylation, the protein migrates to 85-100 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.01 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human APLP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human APLP2 is greater than 95% as determined by SEC-HPLC.

背景(Background)

Amyloid β precursor-like protein 2 (APLP2) has been determined to serve an important role in the progression of a number of cancer types. APLP2 expression was significantly associated with disease-specific survival (P<0.001). APLP2 may be used to potentially predict patient prognosis, and to guide clinical diagnosis and treatment in CCRCC.

分子别名(Synonyms)

APPH; CDEBP; CDEI box-binding; APPL2; YWK-II;

文献(References)

Gao L, Zhao H, Zhang D, Zhou C, Wang H, Ren C, Liu Y, Xia Y, Shi B. Role of APLP2 in the prognosis and clinicopathology of renal cell carcinoma. Oncol Lett. 2019 Jan;17(1):508-513. doi: 10.3892/ol.2018.9577. Epub 2018 Oct 15. PMID: 30655794; PMCID: PMC6313182.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.