AMH-HM2R2 | 价格

AMH-HM2R2-100μg / 询价

AMH-HM2R2-500μg / 询价

AMH-HM2R2-500μgx2 / 询价

Human AMHRII Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human AMHRII Protein is expressed from HEK293 with hFc tag at the C-Terminus.
It contains Pro18-Ser144 [Accession | Q16671-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 40.2 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human AMHRII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human AMHRII is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized Human AMHRII, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-AMHRII Antibody, hFc Tag with the EC50 of 36.7ng/ml determined by ELISA (QC Test).

背景(Background)

The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women undergoing medically assisted reproduction. Three hundred in vitro fertilization or intracytoplasmic sperm injection patients constituted the study population, while 300 women with at least one spontaneous pregnancy participated as controls.

分子别名(Synonyms)

MIS type II receptor; MISRII; MRII; AMHR; MISR2; AMHR2; AMH type II receptor; AMHR2; AMHRII; C14

文献(References)

(1) Lazaros L, Fotaki A, Pamporaki C, Hatzi E, Kitsou C, Zikopoulos A, Virgiliou C, Kosmas I, Bouba I, Stefos T, Theodoridis G, Georgiou I. The ovarian response to standard gonadotropin stimulation is influenced by AMHRII genotypes. Gynecol Endocrinol. 2016 Aug;32(8):641-645. doi: 10.3109/09513590.2016.1149810. Epub 2016 Mar 2. PMID: 26933946.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.