APL-HM0P112-100μg / 询价
APL-HM0P112-100μgx5 / 询价
APL-HM0P112-100μgx10 / 询价
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Human APLNR VLP
Recombinant Human APLNR VLP is expressed from HEK293.It contains Met1-Asp380 (It may have cross reaction with anti-His antibody) [Accession | P35414].
The target protein has a predicted MW of 46.7 kDa.
> 95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS, 200mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human APLNR VLP is greater than 95% as determined by SEC-HPLC.
Immobilized Human APLNR VLP at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-APLNR Antibody, hFc Tag with the EC50 of 0.20μg/ml determined by ELISA (QC Test).
Apelin receptor (APJ), a member of the class A family of G protein-coupled receptor (GPCR), plays a crucial role in regulating cardiovascular and central nervous systems function. APJ influences the onset and progression of various diseases such as hypertension, atherosclerosis, and cerebral stroke, making it an important target for drug development.
Apelin receptor; AGTRL1; APJ; HG11; APJR; AR
Hu S, Wang D, Liu W, Wang Y, Chen J, Cai X. Apelin receptor dimer: Classification, future prospects, and pathophysiological perspectives. Biochim Biophys Acta Mol Basis Dis. 2024 Aug;1870(6):167257. doi: 10.1016/j.bbadis.2024.167257. Epub 2024 May 23. PMID: 38795836.
