BCM-HM107 | 价格

BCM-HM107-100μg / 询价

BCM-HM107-500μg / 询价

BCM-HM107-500μgx2 / 询价

Human BCMA/TNFRSF17 Protein

COA MSDS
产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human BCMA/TNFRSF17 Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Met1-Ala54 [Accession | Q02223-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 7.51 kDa. Due to glycosylation, the protein migrates to 13-23 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Human BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human BCMA is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Human BCMA, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human BAFF, monomeric Fc Tag with the EC50 of 3.8ng/ml determined by ELISA. (QC Test)
 
Immobilized Human BCMA, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Avi Tag with the EC50 of 16.5ng/ml determined by ELISA.
 
Immobilized Human BCMA, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-BCMA Antibody, hFc Tag with the EC50 of 2.6ng/ml determined by ELISA.
背景(Background)

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).

分子别名(Synonyms)

CD269; TNFRSF17; BCMA; BCM; TNFRSF13A

文献(References)

(1) Bossen C , Schneider P. BAFF, APRIL and their receptors: Structure, function and signaling[J]. Seminars in Immunology, 2006, 18(5):0-275.D

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.