BSA-HM101 | 价格

BSA-HM101-100μg / 询价

BSA-HM101-500μg / 询价

BSA-HM101-500μgx2 / 询价

Human Serum Albumin Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human Serum Albumin Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Asp25-Leu609 [Accession | P02768-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 68.08 kDa. Due to glycosylation, the protein migrates to 65-85 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Human Serum Albumin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human Serum Albumin is greater than 95% as determined by SEC-HPLC.
SPR Data
Human Serum Albumin, His Tag immobilized on CM5 Chip can bind Human FcRn, His Tag (Cat. FRN-HM101) with an affinity constant of 1.00 μM as determined in SPR assay (Biacore T200). (QC Test)
背景(Background)

Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier.

分子别名(Synonyms)

Albumin; ALB; Serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341

文献(References)

(1) Ishima Y, Maruyama T. [Human Serum Albumin as Carrier in Drug Delivery Systems]. Yakugaku Zasshi. 2016;136(1):39-47. Japanese. doi: 10.1248/yakushi.15-00227-1. PMID: 26725666.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.