BSA-HM501 | 价格

BSA-HM501-100μg / 询价

BSA-HM501-500μg / 询价

BSA-HM501-500μgx2 / 询价

Human Serum Albumin Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human Serum Albumin Protein is expressed from HEK293 with Llama IgG2b Fc tag at the C-terminus.
It contains Asp25-Leu609 [Accession | P02768-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 93.78 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Human Serum Albumin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human Serum Albumin is greater than 95% as determined by SEC-HPLC.
BLI Data
Loaded Biotinylated Human FcRn, His-Avi Tag on Streptavidin-Biosensor can bind Human Serum Albumin, Llama Fc Tag with an affinity constant of 24.7 nM as determined in BLI assay . (QC Test)
背景(Background)

Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier.

分子别名(Synonyms)

Albumin; ALB; Serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341

文献(References)

(1) Ishima Y, Maruyama T. [Human Serum Albumin as Carrier in Drug Delivery Systems]. Yakugaku Zasshi. 2016;136(1):39-47. Japanese. doi: 10.1248/yakushi.15-00227-1. PMID: 26725666.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.