CD2-HM124V-100μg / 询价
CD2-HM124V-500μg / 询价
CD2-HM124V-500μgx2 / 询价
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Human CD24 Protein-VLP
Recombinant Human CD24 Protein-VLP is expressed from HEK293.It contains Ser27-Gly59 (It may have cross reaction with anti-His antibody) [Accession | P25063-1].
The target protein has a predicted MW of 5.0 kDa.
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20°C or lower for 12 months as supplied from date of receipt.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CD24 VLP at 0.5 μg/ml (100 μl/Well) on the plate. Dose response curve for Anti-CD24 Antibody, hFc Tag with the EC50 of 3.7 ng/ml determined by ELISA (QC Test).
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers.
CD 24; CD24 molecule; CD24A; FLJ22950; FLJ43543; MGC75043
(1) Barkal AA, et al.CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.Nature. 2019 Jul 31. doi: 10.1038/s41586-019-1456-0.D
(2)Sun F, Wang T, Jiang J, et al. Engineering a high-affinity humanized anti-CD24 antibody to target hepatocellular carcinoma by a novel CDR grafting design[J]. Oncotarget, 2017, 8(31):51238-51252.
