CDD-HM101 | 价格

CDD-HM101-100μg / 询价

CDD-HM101-500μg / 询价

CDD-HM101-500μgx2 / 询价

Human CD3D/CD3 delta Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human CD3D/CD3 delta Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Phe22-Ala105 [Accession | P04234-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 10.4 kDa. Due to glycosylation, the protein migrates to 15 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human CD3 delta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human CD3 delta is greater than 95% as determined by SEC-HPLC.

背景(Background)

T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein.In immunology, the CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.

分子别名(Synonyms)

CD3d; CD3D; CD3-DELTA; T3D; CD3 delta; T3DOKT3; CD3-DELTA; IMD19

文献(References)

(1)Penaranda C , Tang Q , Bluestone J A. Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells[J]. The Journal of Immunology, 2011, 187(4):2015-2022.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.