CLD-HM006-100μg / 询价
CLD-HM006-100μg x 5 / 询价
CLD-HM006-100μg x 10 / 询价
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Human Claudin 6 Protein-VLP
Recombinant Full length Human Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220 [Accession | P56747].
The target protein has a predicted MW of 24.5 kDa.
> 95% as determined by HPLC.
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.
Immobilized Human Claudin 6 VLP at 1μg/ml (100μl/Well). Dose response curve for Anti-Claudin 6 Antibody, mFc Tag with the EC50 of 4.8ng/ml determined by ELISA (QC Test).
Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.
Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2
(1) Sugimoto K, Ichikawa-Tomikawa N, Kashiwagi K, Endo C, Tanaka S, Sawada N, Watabe T, Higashi T, Chiba H. Cell adhesion signals regulate the nuclear receptor activity. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24600-24609. doi: 10.1073/pnas.1913346116. Epub 2019 Nov 18. PMID: 31740618; PMCID: PMC6900646.
