CLD-HM10N-100μg / 询价
CLD-HM10N-100μg x 5 / 询价
CLD-HM10N-100μg x 10 / 询价
- 客服电话
- 技术支持
FITC-equivalent Human Claudin 18.2 Protein-Nanodisc
Recombinant FITC-equivalent Human Claudin 18.2 Protein-Nanodisc is expressed from HEK293 with His tag at the N-terminus.It contains Met1-Val261 [Accession | P56856-2].
The protein has a predicted MW of 49.10 kDa.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
FITC-equivalent Human Claudin 18.2 Nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-Claudin18.2 Antibody with an affinity constant of 6.63 nM as determined in SPR assay (Biacore T200) (QC Test).
Claudin18 (CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
CLDN18; CLDN18.2; Claudin-18.2; Claudin18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
(1) Singh P , Toom S , Huang Y. Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer[J]. Journal of Hematology & Oncology, 2017, 10(1):105.
