CLD-HM4N156B-100μg / 询价
CLD-HM4N156B-100μg x 5 / 询价
CLD-HM4N156B-100μg x 10 / 询价
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FITC-equivalent Biotinylated Human Claudin 18.2 Protein-Nanodisc
Recombinant FITC-equivalent Biotinylated Human Claudin 18.2 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus, Avi tag at the N-terminus.It contains Met1-Val261 [Accession | P56856-2].
The protein has a predicted MW of 51.40 kDa.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized FITC-equivalent Biotinylated Human Claudin 18.2 Nanodisc, His Tag at 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-Claudin18.2 Antibody, hFc Tag with the EC50 of 0.49μg/ml determined by ELISA.
Claudin18 (CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
CLDN18; CLDN18.2; Claudin-18.2; Claudin18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
(1) Singh P , Toom S , Huang Y. Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer[J]. Journal of Hematology & Oncology, 2017, 10(1):105.
