CLD-HM52DB-100μg / 询价
CLD-HM52DB-500μg / 询价
CLD-HM52DB-500μgx2 / 询价
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Biotinylated Human CLEC2D Protein
Recombinant Biotinylated Human CLEC2D Protein is expressed from HEK293 with hFc tag and Avi tag at the N-Terminus.It contains Arg60-Val191 [Accession | Q9UHP7-1].
The protein has a predicted MW of 59.1 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human CLEC2D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human CLEC2D is greater than 95% as determined by SEC-HPLC.
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies.
LLT-1; CLAX; LLT1; OCIL; CLEC2D; CLAXLLT-1; OCILmember D
(1) Varaden D, Moodley J, Onyangunga OA, Naicker T. Morphometric image analysis of placental C-type lectin domain family 2, member D (CLEC2D) immuno-expression in HIV associated pre-eclampsia. Eur J Obstet Gynecol Reprod Biol X. 2019 May 8;3:100039. doi: 10.1016/j.eurox.2019.100039. PMID: 31403127; PMCID: PMC6687384.
