COV-VM2S1-100μg / 询价
COV-VM2S1-500μg / 询价
COV-VM2S1-500μgx2 / 询价
SARS-COV-2 Spike S1 Protein
Recombinant SARS-COV-2 Spike S1 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Val16-Arg685.[Accession | QHO60594.1]
The protein has a predicted MW of 101.6 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.
Less than 1EU per μg by the LAL method.
> 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
SARS-COV-2 Spike S1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of SARS-COV-2 Spike S1 is greater than 95% as determined by SEC-HPLC.
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
S1 protein; Spike protein S1; Spike,S1 protein; S glycoprotein Subunit1
(1)Ren W, Sun H, Gao GF, Chen J, Sun S, Zhao R, Gao G, Hu Y, Zhao G, Chen Y, Jin X, Fang F, Chen J, Wang Q, Gong S, Gao W, Sun Y, Su J, He A, Cheng X, Li M, Xia C, Li M, Sun L. Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates. Vaccine. 2020 Jul 31;38(35):5653-5658. doi: 10.1016/j.vaccine.2020.06.066. Epub 2020 Jun 24. PMID: 32651113; PMCID: PMC7311893.
