DLK-CM101 | 价格

DLK-CM101-100μg / 询价

DLK-CM101-500μg / 询价

DLK-CM101-500μgx2 / 询价

Cynomolgus DLK1 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Cynomolgus DLK1 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Ala24-Cys306 [Accession | XP_005562275.1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 31.26 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Cynomolgus DLK1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Cynomolgus DLK1 is greater than 95% as determined by SEC-HPLC.

背景(Background)

paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.

分子别名(Synonyms)

pG2; FA1; DLK; DLK1; DLK-1; Pref1; secredeltin; ZOG

文献(References)

(1) Macedo DB, Kaiser UB. DLK1, Notch Signaling and the Timing of Puberty. Semin Reprod Med. 2019 Jul;37(4):174-181. doi: 10.1055/s-0039-3400963. Epub 2020 Jan 23. PMID: 31972862.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.