FGL-HM211-100μg / 询价
FGL-HM211-500μg / 询价
FGL-HM211-500μgx2 / 询价
Human FGL1 Protein
Recombinant Human FGL1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Asp64-Asn305 [Accession | Q08830].
The protein has a predicted MW of 54.8 kDa. Due to glycosylation, the protein migrates to 60-66 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 90% as determined by HPLC
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in 20mM PB, 250mM NaCl (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human FGL1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human LTBR is greater than 90% as determined by SEC-HPLC.
Immobilized Human LAG3, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human FGL1, hFc Tag with the EC50 of 0.28μg/ml determined by ELISA.
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
FGL1; FGL-1; Hepassocin; HP-041; HFREP-1; LFIRE-1; HFREP1; Lag3 ligand
(1)Wang, J., Sanmamed, M.F., Datar, I., Su, T.T., Ji, L., Sun, J., Chen, L., Chen, Y., Zhu, G., Yin, W., et al. (2019). Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3. Cell 176, 334-347.e312.
