GPC-HM003-100μg / 询价
GPC-HM003-100μg x 5 / 询价
GPC-HM003-100μg x 10 / 询价
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Human GPC3 (438-554) Protein-VLP
Recombinant Human GPC3 (438-554) Protein-VLP is expressed from HEK293.It contains Arg438-Asn554 [Accession | P51654-1].
The target protein has a predicted MW of 21.5 kDa.
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human GPC3 (438-554) VLP is greater than 95% as determined by SEC-HPLC.
Immobilized Human GPC3 (438-554) VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 9.7ng/ml determined by ELISA.
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed.
GPC3; DGSX; Glypican 3; GTR2-2; MXR7; OCI5; OCI-5; SGB; SGBS; SGBS1SDYS; SDYS; SGBS1
(1)Ho M , Kim H. Glypican-3: A new target for cancer immunotherapy[J]. European Journal of Cancer, 2011, 47(3):0-338.
