IL1-HM1R5B-100μg / 询价
IL1-HM1R5B-500μg / 询价
IL1-HM1R5B-500μgx2 / 询价
Biotinylated Human IL-15RA&IL-15 Protein (Primary Amine Labeling)
Recombinant Biotinylated Human IL-15RA&IL-15 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.; It contains Ile31-Ser108 (IL-15RA)&Asn49-Ser162 (IL-15).[Accession | Q13261-1 (IL-15RA)&P40933-1 (IL-15)]
The protein has a predicted MW of 23.8 kDa. Due to glycosylation, the protein migrates to 25-28 kDa&30-35 kDa based on Tris-Bis PAGE result.
Less than 1 EU per ug by the LAL method.
> 95% as determined by Tris-Bis PAGE
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human IL-15RA&IL-15 (Primary Amine Labeling) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Immobilized Human IL-2 R beta, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human IL-15Ra&IL-15, His Tag with the EC50 of 18.5 ng/ml determined by ELISA.
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.
IL-15 R alpha;CD215;IL15RA;IL-15RA;IL-15R-alpha1;Interleukin-15;IL-15;IL15; Nanrilkefusp alfa
(1) Nadeau L, Aguer C. Interleukin-15 as a myokine: mechanistic insight into its effect on skeletal muscle metabolism. Appl Physiol Nutr Metab. 2019 Mar;44(3):229-238. doi: 10.1139/apnm-2018-0022. Epub 2018 Sep 6. PMID: 30189147.
