IL3-HM2RA-100μg / 询价
IL3-HM2RA-500μg / 询价
IL3-HM2RA-500μgx2 / 询价
- 关联产品
- 客服电话
- 技术支持
Human IL-3 R alpha/CD123 Protein
Recombinant Human IL-3 R alpha/CD123 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Thr19-Arg305 [Accession | P26951-1].
The protein has a predicted MW of 59.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
> 90% as determined by Bis-Tris PAGE
> 90% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
CD123; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL3RAY; IL3RX; IL3RY; MGC34174; IL-3 R alpha
(1)Ugo Testa, Elvira Pelosi, Arthur Frankel.CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies.Biomark Res. 2014; 2: 4
