JAM-HM101 | 价格

JAM-HM101-100μg / 询价

JAM-HM101-500μg / 询价

JAM-HM101-500μgx2 / 询价

Human JAML Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human JAML Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Leu20-Leu275 [Accession | NP_001091996.1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 30.1 kDa. Due to glycosylation, the protein migrates to 38-42 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Human JAML on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
背景(Background)

JAML (junctional adhesion molecule-like), contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail. JAML mRNA is expressed in hematopoietic tissues and is prominently expressed in granulocytes. The fact that JAML protein is localized at the cell plasma membrane in the areas of cell-cell contacts, whereas it is not detected at free cell borders, suggests that JAML is engaged in homophilic interactions.

分子别名(Synonyms)

JunctioJAML; AMICA1; AMICA; CREA7-1; Gm638; JAML

文献(References)

(1) Moog-Lutz C, Cavé-Riant F, Guibal FC, Breau MA, Di Gioia Y, Couraud PO, Cayre YE, Bourdoulous S, Lutz PG. JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood. 2003 Nov 1;102(9):3371-8. doi: 10.1182/blood-2002-11-3462. Epub 2003 Jul 17. PMID: 12869515.