KIR-HM4L2-100μg / 询价
KIR-HM4L2-500μg / 询价
KIR-HM4L2-500μgx2 / 询价
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Human KIR2DL2 Protein
Recombinant Human KIR2DL2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245 [Accession | P43627].
The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human KIR2DL2 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human KIR2DL2 is greater than 95% as determined by SEC-HPLC.
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
NKAT-6;p58 NK receptor CL-43;CD158b1;KIR2DL2;CD158B1;NKAT6
(1)Yoon S R , Kim T D , Choi I. Understanding of molecular mechanisms in natural killer cell therapy[J]. Experimental & Molecular Medicine, 2015, 47(2):e141.
