KIR-HM4L5 | 价格

KIR-HM4L5-100μg / 询价

KIR-HM4L5-500μg / 询价

KIR-HM4L5-500μgx2 / 询价

Human KIR2DL5 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human KIR2DL5 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.
It contains His22-His240 [Accession | NP_065396].

分子量大小(Molecular Weight)

The protein has a predicted MW of 26.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human KIR2DL5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

背景(Background)

A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ancestral lineage of KIR with Ig-like domains of the D0-D2 type, of which KIR2DL4, an HLA-G receptor, is the only other human member.

分子别名(Synonyms)

KIR2DL5A; CD158F; CD158F1; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; KIR2DL5B

文献(References)

(1) Cisneros E, Moraru M, Gómez-Lozano N, López-Botet M, Vilches C. KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression. Front Immunol. 2012 Sep 17;3:289. doi: 10.3389/fimmu.2012.00289. PMID: 23060877; PMCID: PMC3443818.