LGR-HM10N-100μg / 询价
LGR-HM10N-100μg x 5 / 询价
LGR-HM10N-100μg x 10 / 询价
Human LGR-4 Protein-Nanodisc
Recombinant Human LGR-4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Ala25-Asp951 [Accession | Q9BXB1-1].
The protein has a predicted MW of 105.80 kDa.
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human R-Spondin 3, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36μg/ml determined by ELISA (QC Test).
Human R Spondin 3, His Tag immobilized on CM5 Chip can bind Human LGR-4 Nanodisc, His Tag with an affinity constant of 0.40 nM as determined in SPR assay (Biacore T200).
Leucine-rich repeat-containing G protein-coupled receptor (LGR)-4 is a G protein-coupled receptor (GPCR) with a seven-transmembrane domain structure. LGRs are evolutionally and structurally phylogenetic, classified into three subgroups and are members of the so-called orphan receptors.
LGR4; GPR48
Kato S, Matsubara M, Matsuo T, Mohri Y, Kazama I, Hatano R, Umezawa A, Nishimori K. Leucine-rich repeat-containing G protein-coupled receptor-4 (LGR4, Gpr48) is essential for renal development in mice. Nephron Exp Nephrol. 2006;104(2):e63-75. doi: 10.1159/000093999. Epub 2006 Jun 19. PMID: 16785743.
