NGF-HM00B-100μg / 询价
NGF-HM00B-500μg / 询价
NGF-HM00B-500μgx2 / 询价
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Human Beta-NGF Protein
Recombinant Human Beta-NGF Protein is expressed from HEK293 without tag.It contains Ser122-Ala241 [Accession | P01138].
The protein has a predicted MW of 13.49 kDa. Due to glycosylation, the protein migrates to 14-18 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in 20mM NaAc, 150mM Nacl (pH 5.5).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human Beta-NGF on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2 - 2 ng/ml.
Nerve growth factor-beta (β-NGF) is a polypeptide growth factor that regulates survival, growth, and differentiation of specific peripheral and central neurons via its high-affinity receptor, tyrosine kinase receptor A (TrKA), and low-affinity receptor, p75 neurotrophin receptor (p75NTR).
NGF; NGFB; Beta NGF; HSAN5;
Sari LM, Zampini R, Argañaraz ME, Carretero MI, Fumuso FG, Barraza DE, Ratto M, Apichela SA. Expression of β-NGF and high-affinity NGF receptor (TrKA) in llama (Lama glama) male reproductive tract and spermatozoa. Mol Reprod Dev. 2018 Dec;85(12):934-944. doi: 10.1002/mrd.23075. Epub 2018 Nov 14. PMID: 30328213.
