NKP-HM146-100μg / 询价
NKP-HM146-500μg / 询价
NKP-HM146-500μgx2 / 询价
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Human NKp46/NCR1/CD335 Protein
Recombinant Human NKp46/NCR1/CD335 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln22-Asn254 [Accession | AAH64806.1].
The protein has a predicted MW of 27.5 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.
>95% as determined by Bis-Tris PAGE
>95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human NKp46 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human NKp46 is greater than 95% as determined by SEC-HPLC.
Immobilized Human NKp46, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 15.0 ng/ml determined by ELISA.
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR). These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094
(1) Glasner A, Isaacson B, Viukov S, et al. Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression.[J]. Sci Rep, 2017, 7(1):13090.
