ROR-HM401-100μg / 询价
ROR-HM401-500μg / 询价
ROR-HM401-500μgx2 / 询价
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Human/Cynomolgus/Rhesus macaque ROR1 Protein
Recombinant Human/Cynomolgus/Rhesus macaque ROR1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln30-Glu403 [Accession | Q01973-1].
The protein has a predicted MW of 44.9 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human/Cynomolgus/Rhesus macaque ROR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human/Cynomolgus/Rhesus macaque ROR1 is greater than 95% as determined by SEC-HPLC.
Immobilized Human/Cynomolgus/Rhesus macaque ROR1, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-ROR1 Antibody, hFc Tag with the EC50 of 1.4ng/ml determined by ELISA.
ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.
ROR1; NTRKR1; dJ537F10.1
(1)Zhang S , Cui B , Lai H , et al. Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy[J]. Proceedings of the National Academy of Sciences, 2014, 111(48):17266-71.
