SEL-HM10P-100μg / 询价
SEL-HM10P-500μg / 询价
SEL-HM10P-500μgx2 / 询价
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Human P-Selectin/CD62P Protein
Recombinant Human P-Selectin/CD62P Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Trp42-Ala771 [Accession | P16109].
The protein has a predicted MW of 81.05 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human P-Selectin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human P-Selectin is greater than 95% as determined by SEC-HPLC.
Immobilized Human P-Selectin, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-P-Selectin Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA (QC Test).
Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells. A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3
(1)Ataga K I , Kutlar A , Kanter J , et al. Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease[J]. New England Journal of Medicine, 2016, 376(5):429-439.
