SLC-HM1ANB-100μg / 询价
SLC-HM1ANB-100μgx5 / 询价
SLC-HM1ANB-100μgx10 / 询价
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表达区间及表达系统(Source)
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Recombinant Biotinylated Human NaPi2b/SLC34A2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu689 [Accession | O95436-2]. |
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分子量大小(Molecular Weight)
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The protein has a predicted MW of 88.6 kDa. |
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内毒素(Endotoxin)
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Less than 1 EU per μg by the LAL method. |
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制剂(Formulation)
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Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells. |
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存储(Storage)
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Valid for 6 months from date of receipt when stored at -80°C. |
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阴性对照
(Recommended Negative Control)
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CON-HM1NB |
Our Styrene-Maleic Anhydride(SMA) nanodisc platform delivers multi-pass transmembrane proteins exactly as they exist in the HEK293 cell membrane following recombinant expression— preserving their endogenous lipid environment and correct conformational states. Isolated directly from HEK293 cells via a gentle, detergent-free process, the multi-pass membrane proteins are subsequently encapsulated by SMA to ensure their stability. These uniform soluble nanoparticles eliminate extraction interferences while maintaining biological activity. Ensuring consistent performance from lot to lot, our nanodiscs provide the reliability and biological relevance essential for antibody screening and functional characterization in therapeutic antibody drug discovery and development, as assessed by SPR, BLI, ELISA, and other standard platforms.
❖ Correct structure & conformation
❖ Functional relevance ensured
❖ His-tag & biotinylation tag available
❖ Antibody screening
❖ Functional characterization(Molecular Level)
❖ Assay: SPR, BLI, ELISA
Recombinant Biotinylated Human NaPi2b/SLC34A2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu689 [Accession | O95436-2].
The protein has a predicted MW of 88.6 kDa.
Less than 1 EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Valid for 6 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
SLC34A2, a member of the SLC34 family, is a multipass membrane protein and encodes a type 2b sodium-dependent phosphate transporter, NaPiIIb. It is known that SLC34A2 can mediate transporting inorganic phosphate into epithelial cells via sodium ion cotransport. SLC34A2 also strongly inhibited tumor growth and metastasis ability in an A549 subcutaneous tumor model and lung metastasis mode.
NaPi-2b; NaPi 2b; NAPI-IIb; NPTIIb; NaPi2b; PULAM;
Li Y, Chen X, Lu H. Knockdown of SLC34A2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Invasion. Oncol Res. 2016 Oct 27;24(6):511-519. doi: 10.3727/096504016X14719078133483. PMID: 28281971; PMCID: PMC7838622.
SLC-HM1ANB-100μg / 询价
SLC-HM1ANB-100μgx5 / 询价
SLC-HM1ANB-100μgx10 / 询价
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