STP-HM00VB-100μg / 询价
STP-HM00VB-100μgx5 / 询价
STP-HM00VB-100μgx10 / 询价
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Biotinylated Human STEAP1 VLP
Recombinant Biotinylated Human STEAP1 VLP is expressed from HEK293.It contains Met1-Leu339 (It may have cross reaction with anti-His antibody) [Accession | Q9UHE8].
The protein has a predicted MW of 43.06 kDa.
> 95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS, 300mM L-Arginine (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Biotinylated Human STEAP1 VLP is greater than 95% as determined by SEC-HPLC.
Immobilized Biotinylated Human STEAP1 VLP at 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Vandortuzumab, hFc Tag with the EC50 of 91.2ng/ml determined by ELISA. (QC Test)
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III).
PRSS24; STEAP; PRSS24, STEAP 1
Oosterheert W, Gros P. Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1). J Biol Chem. 2020 Jul 10;295(28):9502-9512. doi: 10.1074/jbc.RA120.013690. Epub 2020 May 14. PMID: 32409586; PMCID: PMC7363144.
