货号价格

STR-HM1N1-100μg / 询价

STR-HM1N1-500μg / 询价

STR-HM1N1-500μgx2 / 询价

Human SSTR2 Protein-Nanodisc

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human SSTR2 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.
It contains Met1-Ile369 [Accession | P30874-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 42.70 kDa.

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
ELISA Data

Immobilized Human SSTR2 Nanodisc, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-SSTR2 Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA (QC Test).

SPR Data

Human SSTR2 Nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-SSTR2 Antibody, hFc Tag with an affinity constant of 91.88 pM as determined in SPR assay (Biacore T200).

背景(Background)

Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma.

分子别名(Synonyms)

SS-2-R; SS2-R; SS2R; SRIF-1; SRIF1; SRIF 1; Smstr2; SST2; SSTR2

文献(References)

Wu W, Zhou Y, Wang Y, Liu L, Lou J, Deng Y, Zhao P, Shao A. Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma. Front Oncol. 2020 Sep 3;10:1633. doi: 10.3389/fonc.2020.01633. PMID: 33014821; PMCID: PMC7494964.