TEM-HM17R | 价格

TEM-HM17R-100μg / 询价

TEM-HM17R-500μg / 询价

TEM-HM17R-500μgx2 / 询价

Human TEM7R/PLXDC2 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human TEM7R/PLXDC2 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Lys31-Ala454 [Accession | Q6UX71-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 49.05 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human TEM7R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human TEM7R is greater than 95% as determined by SEC-HPLC.

背景(Background)

Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres.

分子别名(Synonyms)

PLXDC2; TEM7R;

文献(References)

(1) Kondkar AA, Sultan T, Almobarak FA, Kalantan H, Abu-Amero KK, Al-Obeidan SA. Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort. BMC Res Notes. 2018 Oct 16;11(1):733. doi: 10.1186/s13104-018-3848-x. PMID: 30326957; PMCID: PMC6192173.

(2) Miller-Delaney SF, Lieberam I, Murphy P, Mitchell KJ. Plxdc2 is a mitogen for neural progenitors. PLoS One. 2011 Jan 21;6(1):e14565. doi: 10.1371/journal.pone.0014565. PMID: 21283688; PMCID: PMC3024984.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.