TGF-HM5R2-100μg / 询价
TGF-HM5R2-500μg / 询价
TGF-HM5R2-500μgx2 / 询价
Human TGF-beta RII/TGFBR2 Protein
Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Ile24-Asp159.[Accession | P37173-1]
The protein has a predicted MW of 44.2 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Tris-Bis PAGE result.
Less than 1EU per μg by the LAL method.
> 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3-6 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TGF-beta RII on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TGF-beta RII is greater than 95% as determined by SEC-HPLC.
Immobilized Human Mature TGF beta 1, No Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human TGF-beta RII, hFc Tag with the EC50 of 7.7ng/ml determined by ELISA (QC Test).
Human TGF-beta RII, hFc Tag captured on CM5 Chip via Protein A can bind Human Latent TGF beta 2, His Tag with an affinity constant of 2.21 μM as determined in SPR assay (Biacore T200).
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II
(1)Fricke F, Lee J, Michalak M, et al. TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells. Cell Commun Signal. 2017;15(1):14. Published 2017 Apr 4. doi:10.1186/s12964-017-0169-y.
