THR-HM00V | 价格

THR-HM00V-100μg / 询价

THR-HM00V-100μgx5 / 询价

THR-HM00V-100μgx10 / 询价

Human TSHR VLP

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human TSHR VLP is expressed from HEK293.
It contains Met1-Leu764 (It may have cross reaction with anti-His antibody) [Accession | P16473].

分子量大小(Molecular Weight)

The target protein has a predicted MW of 87.81 kDa.

纯度(Purity)

> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22μm filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
SEC-HPLC

The purity of Human TSHR VLP is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized Human TSHR VLP at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-TSHR Antibody, hFc Tag with the EC50 of 56.5ng/ml determined by ELISA. (QC Test)

背景(Background)

Thyroid stimulating hormone receptor (TSHR) is a receptor for thyrostimulin and thyroid stimulating hormone (TSH, also called thyrotropin). TSHR is a cell surface glycoprotein receptor and belongs to the leucine-rich repeat (LGR) subfamily of G-protein-coupled receptors (GPCRs).

分子别名(Synonyms)

TSH-R; LGR3; TSH R

文献(References)

Chu YD, Yeh CT. The Molecular Function and Clinical Role of Thyroid Stimulating Hormone Receptor in Cancer Cells. Cells. 2020 Jul 20;9(7):1730. doi: 10.3390/cells9071730. PMID: 32698392; PMCID: PMC7407617.