TSF-HM001-100μg / 询价
TSF-HM001-500μg / 询价
TSF-HM001-500μgx2 / 询价
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Human TM4SF1 Protein-VLP
Recombinant Human TM4SF1 Protein-VLP is expressed from HEK293.It contains Met1-Cys202 [Accession | P30408].
Human TM4SF1 Protein has a predicted MW of 51.50 kDa.
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human TM4SF1 VLP is greater than 95% as determined by SEC-HPLC.
Immobilized Human TM4SF1 VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-TM4SF1 Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA.
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
M3S1; TAAL6; H-L6; L6
Yang JC, Zhang Y, He SJ, Li MM, Cai XL, Wang H, Xu LM, Cao J. TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. Sci Rep. 2017 Apr 3;7:45895. doi: 10.1038/srep45895. PMID: 28368050; PMCID: PMC5377454.
