TSF-HM00N-100μg / 询价
TSF-HM00N-100μg x 5 / 询价
TSF-HM00N-100μg x 10 / 询价
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FITC-equivalent Human TM4SF1 Protein-Nanodisc
Recombinant FITC-equivalent Human TM4SF1 Protein-Nanodisc is expressed from HEK293 with His tag at the N-terminus.It contains Met1-Cys202 [Accession | P30408].
The protein has a predicted MW of 51.80 kDa.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized FITC-equivalent Human TM4SF1 Nanodisc, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-TM4SF1 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA (QC Test).
FITC-equivalent Human TM4SF1 Nanodisc, His Tag captured on CM5 Chip via Anti-his antibody can bind Anti-TM4SF1 Antibody with an affinity constant of 0.54 nM as determined in SPR assay (Biacore T200).
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
M3S1; TAAL6; H-L6; L6
Yang JC, Zhang Y, He SJ, Li MM, Cai XL, Wang H, Xu LM, Cao J. TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. Sci Rep. 2017 Apr 3;7:45895. doi: 10.1038/srep45895. PMID: 28368050; PMCID: PMC5377454.
