TSF15-HM4N174B-100μg / 询价
TSF15-HM4N174B-100μg x 5 / 询价
TSF15-HM4N174B-100μg x 10 / 询价
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Biotinylated Human TM4SF15 Protein-Nanodisc
Recombinant Biotinylated Human TM4SF15 Protein-Nanodisc is expressed from HEK293 with His tag at the N-terminus and Avi tag at the C-terminus.It contains Met1-Asn294 [Accession | O95858].
The protein has a predicted MW of 36.9 kDa.
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human TM4SF15 Nanodisc, His Tag at 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-TM4SF15 Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA (QC Test).
Tetraspanin 15 (Tspan15) is identified as an ADAM10-interacting protein to induce selective N-cadherin cleavage. Tspan15 belongs to a family of six tetraspanins (Tspan5, Tspan10, Tspan14, Tspan15, Tspan17, and Tspan33) that have been identified as specific ADAM10-interacting protein partners.
Tetraspanin-15; Tspan-15; Tspan 15; Tetraspan NET-7; TSPAN15; NET7
Barbaud A, Lascombe I, Péchery A, Arslan S, Kleinclauss F, Fauconnet S. GW501516-Mediated Targeting of Tetraspanin 15 Regulates ADAM10-Dependent N-Cadherin Cleavage in Invasive Bladder Cancer Cells. Cells. 2024 Apr 19;13(8):708. doi: 10.3390/cells13080708. PMID: 38667323; PMCID: PMC11049359.
