TSP-CM10R-100μg / 询价
TSP-CM10R-500μg / 询价
TSP-CM10R-500μgx2 / 询价
Cynomolgus TSLPR Protein
Recombinant Cynomolgus TSLPR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Lys231 [Accession | XP_045239630.1].
The protein has a predicted MW of 25.42 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus TSLPR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus TSLPR is greater than 95% as determined by SEC-HPLC.
Immobilized Cynomolgus TSLPR, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus TSLP, His Tag with the EC50 of 0.12μg/ml determined by ELISA (QC Test).
Immobilized Cynomolgus TSLPR, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 13.3ng/ml determined by ELISA.
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
TSLP receptor; TSLPR; CRL2; CRLF2Y; CRLF2; IL-XR; p2RY8/CRLF2 fusion; CRLF2
(1)Blagoev B, Nielsen MM, Angrist M, Chakravarti A, Pandey A. Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene. Gene. 2002 Feb 6;284(1-2):161-8. doi: 10.1016/s0378-1119(02)00380-3. PMID: 11891057.
