AFP-CM101-100μg / 询价
AFP-CM101-500μg / 询价
AFP-CM101-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Cynomolgus AFP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg19-Val609 [Accession | A0A2K5U7U0]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 67.53 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result. |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
制剂(Formulation)
|
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
重构方法(Reconstitution)
|
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Cynomolgus AFP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg19-Val609 [Accession | A0A2K5U7U0].
The protein has a predicted MW of 67.53 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.
Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; HPAFP; AFPD; FETA
(1) Pak VN. The use of alpha-fetoprotein for the treatment of autoimmune diseases and cancer. Ther Deliv. 2018 Jan;9(1):37-46. doi: 10.4155/tde-2017-0073. PMID: 29216804.
AFP-CM101-100μg / 询价
AFP-CM101-500μg / 询价
AFP-CM101-500μgx2 / 询价
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