BH7-HM176-100μg / 询价
BH7-HM176-500μg / 询价
BH7-HM176-500μgx2 / 询价
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Human B7-H6/NCR3LG1 Protein
Recombinant Human B7-H6/NCR3LG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp25-Ser262 [Accession | Q68D85-1].
The protein has a predicted MW of 27.8 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; NCR3LG1; B7 Homolog 6
(1)Wu M R , Zhang T , Gacerez A T , et al. B7H6-Specific Bispecific T Cell Engagers Lead to Tumor Elimination and Host Antitumor Immunity[J]. The Journal of Immunology, 2015, 194(11):5305-5311.
