CD3-HM123 | 价格

CD3-HM123-100μg / 询价

CD3-HM123-500μg / 询价

CD3-HM123-500μgx2 / 询价

Human CD23/Fc epsilon RII Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human CD23/Fc epsilon RII Protein is expressed from HEK293 with His tag at the N-Terminus.
It contains Asp48-Ser321 [Accession | P06734-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 31.8 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human CD23 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human CD23 is greater than 95% as determined by SEC-HPLC.

背景(Background)

CD23 is the low-affinity receptor for immunoglobulin (Ig)E and plays important roles in the regulation of IgE responses. CD23 can be cleaved from cell surfaces to yield a range of soluble CD23 (sCD23) proteins that have pleiotropic cytokine-like activities.

分子别名(Synonyms)

BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF; FCER2; FcεRII; Fcr; Fcgr; Fc receptor; CLEC-6; CLECSF8; MCL; MGC40078; MPCL; Fcer2a; Ly-42

文献(References)

(1)Liu C, Richard K, Wiggins M, Zhu X, Conrad DH, Song W. CD23 can negatively regulate B-cell receptor signaling. Sci Rep. 2016 May 16;6:25629. doi: 10.1038/srep25629. PMID: 27181049; PMCID: PMC4867583.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.