FSF-HM215-100μg / 询价
FSF-HM215-500μg / 询价
FSF-HM215-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Human TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Leu72-Leu251 [Accession | O95150-1]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 44.87 kDa. Due to glycosylation, the protein migrates to 48-60 kDa based on Bis-Tris PAGE result. |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
制剂(Formulation)
|
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
重构方法(Reconstitution)
|
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Human TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Leu72-Leu251 [Accession | O95150-1].
The protein has a predicted MW of 44.87 kDa. Due to glycosylation, the protein migrates to 48-60 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 90% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A
(1)Valatas V, Kolios G, Bamias G. TL1A (TNFSF15) and DR3 (TNFRSF25): A Co-stimulatory System of Cytokines With Diverse Functions in Gut Mucosal Immunity. Front Immunol. 2019;10:583. Published 2019 Mar 27. doi:10.3389/fimmu.2019.00583
FSF-HM215-100μg / 询价
FSF-HM215-500μg / 询价
FSF-HM215-500μgx2 / 询价
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