IL2-MM2RA-100μg / 询价
IL2-MM2RA-500μg / 询价
IL2-MM2RA-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Mouse IL-20RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val33-Lys253 [Accession | Q6PHB0]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result. |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
制剂(Formulation)
|
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
重构方法(Reconstitution)
|
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Mouse IL-20RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val33-Lys253 [Accession | Q6PHB0].
The protein has a predicted MW of 52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA.
IL-20R-alpha; IL-20RA; CRF2-8; IL-20R1; ZcytoR7; FLJ40993
(1) Yu D, Yang X, Lin J, Cao Z, Lu C, Yang Z, Zheng M, Pan R, Cai W. Super-Enhancer Induced IL-20RA Promotes Proliferation/Metastasis and Immune Evasion in Colorectal Cancer. Front Oncol. 2021 Jul 15;11:724655. doi: 10.3389/fonc.2021.724655. PMID: 34336707; PMCID: PMC8319729.
IL2-MM2RA-100μg / 询价
IL2-MM2RA-500μg / 询价
IL2-MM2RA-500μgx2 / 询价
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