货号价格

KIR-HM2L4-100μg / 询价

KIR-HM2L4-500μg / 询价

KIR-HM2L4-500μgx2 / 询价

Human KIR2DL4/CD158d Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human KIR2DL4/CD158d Protein is expressed from HEK293 with hFc tag at the C-terminus. It contains Trp22-His242.[Accession | Q99706-1]

分子量大小(Molecular Weight)

The protein has a predicted MW of 50.24 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

纯度(Purity)

> 90% as determined by Tris-Bis PAGE

制剂(Formulation)

Supplied as 0.22 μm filtered solution in 20mM PB, 500mM NaCl, 200mM L-Arginine (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Tris-Bis PAGE

Human KIR2DL4 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

ELISA Data

Immobilized Human HLA-G Free Heavy Chain, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human KIR2DL4, hFc Tag with the EC50 of 43.4ng/ml determined by ELISA.

背景(Background)

KIR2DL4 is an unusual killer cell immunoglobulin-like receptor (KIR) family member in terms of its structure, expression, cellular localization, and signaling properties. The most conserved KIR in evolution, it is referred to as a framework KIR gene and is expressed by all natural killer (NK) cells and a subset of T cells.

分子别名(Synonyms)

G9P; KIR2DL4; CD158d; KIR-103AS; KIR103AS

文献(References)

Rajagopalan S, Long EO. KIR2DL4 (CD158d): An activation receptor for HLA-G. Front Immunol. 2012 Aug 20;3:258. doi: 10.3389/fimmu.2012.00258. PMID: 22934097; PMCID: PMC3422731.