KLB-MM101-100μg / 询价
KLB-MM101-500μg / 询价
KLB-MM101-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Phe53-Pro994.[Accession | Q99N32-1] |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result. |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
纯度(Purity)
|
> 90% as determined by Tris-Bis PAGE |
制剂(Formulation)
|
Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
存储(Storage)
|
Valid for 12 months from date of receipt when stored at -80°C. |
Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Phe53-Pro994.[Accession | Q99N32-1]
The protein has a predicted MW of 109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
Less than 1EU per μg by the LAL method.
> 90% as determined by Tris-Bis PAGE
> 90% as determined by HPLC
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
betaKlotho; beta-klotho; BKL; KLB; klotho beta like; Klotho beta; MGC142213;βKlotho; β-klotho; klotho β like; Klotho β
(1)Bono BS, Koziel Ly NK, Miller PA, Williams-Ikhenoba J, Dumiaty Y, Chee MJ. Spatial distribution of beta-klotho mRNA in the mouse hypothalamus, hippocampal region, subiculum, and amygdala. J Comp Neurol. 2022 Feb 10. doi: 10.1002/cne.25306. Epub ahead of print. PMID: 35143049.
KLB-MM101-100μg / 询价
KLB-MM101-500μg / 询价
KLB-MM101-500μgx2 / 询价
货号* | 规格* | 名称 | 数量* | |
---|---|---|---|---|
货号* | 名称 | 批号* | |
---|---|---|---|