STP-CM00V | 价格

STP-CM00V-100μg / 询价

STP-CM00V-500μg / 询价

STP-CM00V-500μgx2 / 询价

Cynomolgus STEAP1 VLP

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Cynomolgus STEAP1 VLP is expressed from HEK293.
It contains Met1-Leu339 (It may have cross reaction with anti-His antibody) [Accession | XP_073892701.1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 43.1 kDa.

纯度(Purity)

> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

阴性对照(Recommended Negative Control)
STP-HM0VC
产品数据(Assay Data)
SEC-HPLC
The purity of Cynomolgus STEAP1 VLP is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Cynomolgus STEAP1 at 5 μg/ml (100μl/well) on the plate. Dose response curve for Vandortuzumab, hFc Tag with the EC50 of 36.7 ng/ml determined by ELISA. (QC Test)
背景(Background)

Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface protein of the STEAP family whose main function focuses on intercellular communication and cell growth. STEAP1 is is associated with tumor invasiveness and progression. It is considered a promising putative biomarker and a candidate target for prostate cancer treatment.

分子别名(Synonyms)

PRSS24; STEAP; PRSS24, STEAP 1

文献(References)

Carvalho M, Gomes RM, Moreira Rocha S, Barroca-Ferreira J, Maia CJ, Guillade L, Correa-Duarte MA, Passarinha LA, Moreira FTC. Development of a novel electrochemical biosensor based on plastic antibodies for detection of STEAP1 biomarker in cancer. Bioelectrochemistry. 2023 Aug;152:108461. doi: 10.1016/j.bioelechem.2023.108461. Epub 2023 May 9. PMID: 37192590.