CLE-HM12AF-100μg / 询价
CLE-HM12AF-500μg / 询价
CLE-HM12AF-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant FITC-Labeled Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His65-Ala265 [Accession | Q5QGZ9-2]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 24.6 kDa. Due to glycosylation, the protein migrates to 35-55 kDa based on Bis-Tris PAGE result. |
波长(Wavelength)
|
Excitation Wavelength: 490 nm Emission Wavelength: 520 nm |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
制剂(Formulation)
|
Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
存储(Storage)
|
Valid for 12 months from date of receipt when stored at -80°C. |
Recombinant FITC-Labeled Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His65-Ala265 [Accession | Q5QGZ9-2].
The protein has a predicted MW of 24.6 kDa. Due to glycosylation, the protein migrates to 35-55 kDa based on Bis-Tris PAGE result.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.
MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2
(1)Bill M, Aggerholm A, Kjeldsen E, Roug AS, Hokland P, Nederby L. Revisiting CLEC12A as leukaemic stem cell marker in AML: highlighting the necessity of precision diagnostics in patients eligible for targeted therapy. Br J Haematol. 2019 Mar;184(5):769-781. doi: 10.1111/bjh.15711. Epub 2018 Dec 5. PMID: 30520015.
CLE-HM12AF-100μg / 询价
CLE-HM12AF-500μg / 询价
CLE-HM12AF-500μgx2 / 询价
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